Beta Glucan Lowers Blood Lipids
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BERLIN—Barley beta-glucan reduces serum lipid levels, according to research presented in April at
the First International Congress on Pre-Diabetes and Metabolic Syndrome.
In the six-week study, 76 men and 79 women with hypercholesterolemia, aged
25 to 73, completed a four-week lowfat diet prior to baseline. At the beginning of the trial,
test subjects were randomly allocated to one of four treatment groups or a control group and assayed for
blood lipids and other cardiovascular disease (CVD) biomarkers. During the course of the study, test groups
were administered 3 g and 5 g doses of low molecular weight (LMW) or high molecular weight (HMW) barley
beta-glucan (from Cargill) twice daily, in cereal and juice.
Posttreatment assessment of blood lipids and other CVD biomarkers revealed improvements in
low-density lipoprotein (LDL) cholesterol, triglycerides, markers of glycemic control
(glycosylated hemoglobin, HOMA model) and a key marker of inflammation
The researchers concluded both doses of LMW and HMW barley beta-glucan improved blood lipids over
a six-week treatment period.
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